
Are You Maximizing Management of DEEs? Addressing Diagnostic Delays, Suboptimal Treatment, and Quality of Life
PROGRAM CHAIR

Scott Demarest, MD, MSCS
Chief Precision Medicine Officer
Precision Medicine Institute
Children’s Hospital Colorado
Associate Professor
Departments of Pediatrics and Neurology
University of Colorado School of Medicine
Anschutz Medical Campus
Aurora, Colorado
PROGRAM OVERVIEW
This online activity, led by expert faculty, focuses on equipping clinicians with tools for accurate diagnosis and genetic testing to identify developmental and epileptic encephalopathies (DEEs). The program reviews current pharmacologic agents for managing various DEEs, evaluates comorbid conditions and non-seizure symptoms impacting patients’ daily lives, and addresses strategies for seamless transitions of care from infancy through adulthood.
TARGET AUDIENCE
This activity is designed to meet the educational needs of epileptologists. Adult and pediatric neurologists, PCPs, and advanced practice professionals (NP/PA) may also benefit from the education.
LEARNING OBJECTIVES
Upon the completion of this program, attendees should be able to:
- Describe diagnostic tools and best practices for genetic testing to accurately identify DEEs and specific causative mutations
- Assess the clinical efficacy and safety data for current and emerging therapies to inform personalized treatment selection
- Summarize the comorbid conditions and symptoms beyond seizures that impact patient QoL and how to manage them
JOINT ACCREDITATION STATEMENT
In support of improving patient care, Med Learning Group is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.
PHYSICIAN CREDIT DESIGNATION STATEMENT
Med Learning Group designates this enduring activity for a maximum of 1.0 AMA PRA Category 1 CreditTM. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
NURSES (ANCC) CREDIT DESIGNATION
Med Learning Group designates this activity for a maximum of 1.0 ANCC contact hour.
AAPA CREDIT DESIGNATION STATEMENT – ENDURING MATERIALS
Med Learning Group has been authorized by the American Academy of Physician Associates (AAPA) to award AAPA Category 1 CME credit for activities planned in accordance with AAPA CME Criteria.
This activity is designated for 1.0 AAPA Category 1 CME credit. Approval is valid until December 5, 2026. PAs should only claim credit commensurate with the extent of their participation.
ACCME INNOVATION PARTNER
Med Learning Group (MLG) is proud to be recognized as an ACCME Innovation Partner, leading the way in simplifying CME for physicians. As an Innovation Partner, MLG will be working with the ACCME by submitting credits directly to CME Passport.
PHYSICIAN DISCLAIMER: Upon your acceptance in the evaluation and completion of this CME activity, Med Learning Group will share your completion information and certain personal details (e.g., name, National Provider Identifier, birthdate MM/DD) with the ACCME for inclusion in your CME Passport transcript and, as applicable, reporting to certifying, licensing, or other regulatory authorities you specify.
DISCLOSURE POLICY STATEMENT
In accordance with the Accreditation Council for Continuing Medical Education (ACCME) Standards for Integrity and Independence in Accredited Continuing Education, educational programs sponsored by Med Learning Group must demonstrate balance, independence, objectivity, and scientific rigor. All faculty, authors, editors, staff, and planning committee members participating in an MLG-sponsored activity are required to disclose any relevant financial interest or other relationship with the manufacturer(s) of any commercial product(s) and/or provider(s) of commercial services that are discussed in an educational activity.
DISCLOSURE OF RELEVANT FINANCIAL RELATIONSHIPS
| Faculty Member | Disclosures |
| Scott Demarest, MD | Consulting Fees: BioMarin, Neurogene, Marinus, Taysha, Ultragenyx, UCB, Capsida Biotherapeutics, Mahzi Therapeutics, Biogen, Praxis Precision Medicines, Neurocrine Biosciences, AlphaRose Therapeutics, Azafaros, and Lundbeck. Dr. Demarest receives funding from the NIH, Project 8p, Batten Disease Support & Research Association, and Mila's Miracle Foundation. Dr. Demarest also serves on advisory boards for the non-profit foundations Rare-X, SLC6A1 Connect, Project 8p, Ring14 USA, FamilieSCN2A, Inchstone, and N=1 Collaborative. The Precision Medicine Institute at Children's Hospital Colorado has ongoing partnerships with Illumina, from which Dr. Demarest receives no direct compensation. |
All relevant financial relationships have been mitigated.
Content Review
The content of this activity was independently peer reviewed by a physician and nurse reviewer.
Individuals in Control of the Content of the Activity
The individuals in control of the content of this activity have reported the following financial relationships or relationships to products or devices they have with ineligible companies related to the content of this CE activity:
- Matthew Frese, MBA, General Manager of Med Learning Group, has nothing to disclose.
- Lauren Welch, MA, Sr VP of Operations for Med Learning Group, has nothing to disclose.
- Tom Bregartner, MBA, VP of Outcomes and Accreditation for Med Learning Group, has nothing to disclose.
- Chris Drury, MA, MS, MBA, Medical Director for Med Learning Group, has nothing to disclose.
- La Donna Lue Winston, MSN, APRN, AGACNP-BC, SCRN, RN, has nothing to disclose.
- A medical reviewer from CME Peer Review LLC, has nothing to disclose.
- Andi Koral, MS, CMP-HC, Program Manager for Med Learning Group, has nothing to disclose.
- Russie Allen, MS, Accreditation and Outcomes Manager, for Med Learning Group, has nothing to disclose.
- Jacquelyn Sandfort, Associate Program Manager for Med Learning Group, has nothing to disclose.
DISCLOSURE OF UNLABELED USE
Med Learning Group requires that faculty participating in any CE activity disclose to the audience when discussing any unlabeled or investigational use of any commercial product or device not yet approved for use in the United States. During this lecture, the faculty may mention the use of medications for both FDA-approved and non-approved indications.
METHOD OF PARTICIPATION
There are no fees for participating and receiving CE credit for this activity. In order to obtain your certificate for the mentioned accreditation, participants need to successfully complete the associated pre/post activities and evaluation. Your certificate will be provided as a downloadable file.
DISCLAIMER
Med Learning Group makes every effort to develop CE activities that are science based. This activity is designed for educational purposes. Participants have a responsibility to use this information to enhance their professional development in an effort to improve patient outcomes. Conclusions drawn by the participants should be derived from careful consideration of all available scientific information. The participant should use his/her clinical judgment, knowledge, experience, and diagnostic decision making before applying any information, whether provided here or by others, for any professional use.
For CE questions, please contact Med Learning Group at info@medlearninggroup.com
Contact this CE provider at Med Learning Group for privacy and confidentiality policy statement information at http://medlearninggroup.com/privacy-policy/
AMERICANS WITH DISABILITIES ACT
Event staff will be glad to assist you with any special needs (eg, physical, dietary, etc). Please contact Med Learning Group prior to participating at info@medlearninggroup.com
RELEASED DATE: January 09, 2026
EXPIRATION DATE: January 09, 2027

Copyright © 2025 Med Learning Group. All rights reserved. These materials may be used for personal use only. Any rebroadcast, distribution, or reuse of this presentation or any part of it in any form for other than personal use without the express written permission of Med Learning Group is prohibited.
